Grey's Anatomy has been around for over a decade, and some of its characters have gotten their own TV shows, with three Grey's Anatomy spin off series connecting to the main series. Created by Shonda Rhimes, Grey's Anatomy debuted on ABC in 2005 as a mid-season replacement but was so well-received that it continued its course. The series premiered its 19th season in 2022 and shows no signs of slowing down. Grey's Anatomy follows the basic premise of medical dramas, telling the stories of surgical interns, residents, and attendings as they do their best to balance their personal and professional lives, which end up overlapping most of the time.
The series was led by Meredith Grey (Ellen Pompeo), one of the few characters from season 1 that lasted to season 19 before she departed her own show. Many other characters either left Grey Sloan Memorial Hospital (formerly Seattle Grace Hospital) or have been killed. Some of these characters received a Grey's spin off, some more popular than others. There has been three Grey's Anatomy spin off series, and some of these have had crossover storylines with the main series. They relate to the original series through everything from characters to the city of Seattle to the show's Grey Sloan Memorial Hospital setting.
The first Grey's Anatomy spin off series was Private Practice, which followed Dr. Addison Montgomery (Kate Walsh) after she left Seattle Grace Hospital in order to join a private practice in Los Angeles. The series was set at Seaside Health & Wellness Center (formerly Oceanside Wellness Group), and had five crossover storylines with Grey's Anatomy. Private Practice ended in 2013 after six seasons, with the character of Amelia Shepherd (Caterina Scorsone), Derek's sister, later joining Grey's Anatomy as a series regular.
The second Grey's Anatomy spin off is Station 19, which, even though it is also set in Seattle, has nothing to do with hospitals. Instead, Station 19 focuses on the lives of the women and men at Seattle Fire Station 19, and it stars Jaina Lee Ortiz, Jason George, Grey Damon, Barrett Doss, and more. The series was introduced in Grey's Anatomy's season 14, specifically in episode 13, when firefighters were brought to Grey Sloan Memorial Hospital after a fire. Unlike Private Practice, this spin-off show is still going, with Station 19 season 6 premiering on October 6, 2022.
The third Greay's Anatomy spin off series is Grey's Anatomy: B-Team. This series didn't take viewers outside Grey Sloan Memorial, focusing on a group of interns at the hospital. B-Team was only six episodes long and released as a web series, and its main characters were Dahlia Qadri (Sophia Taylor Ali), Levi Schmitt (Jake Borelli), Casey Parker (Alex Blue Davis), Taryn Helm (Jaicy Elliot), Vik Roy (Rushi Kota), and Sam Bello (Jeanine Mason). B-Team also had special guests from the main series, like Justin Chambers' Alex Karev and Kevin McKidd's Owen Hunt.
Naturally, the Grey's Anatomy spin off series overlapped with the original series from time to time, except for Grey's Anatomy: B-Team, which never crossed over at all. There were 45 crossover episodes that Grey's Anatomy spin offs shared with the main series on regular network television:
As Grey's Anatomy continues bringing more and more stories, it wouldn't be surprising if it gets more spin-offs, and its options are not limited to a single location or city if these three shows are anything to go by. The show will also have to expand its storytelling beyond Meredith Grey after Ellen Pompeo's post-season 19 exit.
The one Grey's Anatomy spin off series that has been talked about, but hasn't happened is one involving characters Jackson (Jesse Williams) and April (Sarah Drew). Nicknamed Japril by fans, both Williams and Drew have talked about this possible spin off of Grey's Anatomy. Jackson and April had several struggles on the show, but in the end, they left the series to start a life together in Boston. They reappeared on Grey's Anatomy's 400th episode, still together.
Drew told reporters in 2021 that she would love for Japril to get back together for a Grey's Anatomy spin off series (via US Weekly). "How amazing and needed is a show about racial justice in the medical field and inequity and equality. How amazing would that be?" ABC Entertainment and Hulu Originals President Craig Erwich said they are always looking to service the fans, but "There are no conversations about a spinoff of Grey's Anatomy at this time." However, both Williams and Drew said they would sign on if ABC wanted it.