as a child, first in commercials and then as a TV actor. Over the years, she has had central roles in everything from "8 Simple Rules" to "The Flight Attendant" and "Harley Quinn." Of course, Cuoco has become arguably most associated with her lead role in the long-running CBS sitcom "The Big Bang Theory," in which she plays Penny, a woman who lives opposite and becomes intertwined in the lives of her fellow series leads, Leonard Hofstadter (Johnny Galecki) and Sheldon Cooper (Jim Parsons).

Relative to Cuoco's practically lifelong acting career, — he was cast in his first few notable roles all in his 30s, including a Quiznos commercial in 2003 that effectively introduced him to TV audiences. That said, he began to portray Sheldon Cooper on "The Big Bang Theory" just four years after his notorious Quiznos commercial, quickly cementing himself as a TV mainstay and a household name.

With all this in mind, published a profile of Cuoco in February of 2021 that includes various quotes from the actor about the time she spent filming the 12 seasons that comprise "The Big Bang Theory.

" Among a number of other insights, Cuoco shared her perspective in the interview on what it was like to work opposite Parsons, and her characterization of her talented co-star confirms everything we always suspected.

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